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Scientists find that a vitamin K precursor (menadione) offers a highly targeted way to kill prostate cancer cells.
It could give us a way to fight one of the most resistant forms of cancer.
Unlike traditional treatments that push cancer into dormancy, menadione acts as a pro-oxidant, disrupting a key lipid called PI(3)P. This lipid helps cells manage waste, and without it, cancer cells become overwhelmed and ultimately burst.
The study, published in Science, demonstrated significant tumor suppression in both mice and human cancer cells. Researchers believe this method could offer a safer and more definitive resolution for prostate cancer while minimizing the risk of resistance.
Beyond cancer, menadione also shows promise in treating X-linked myotubular myopathy, a severe genetic muscle disorder. Importantly, menadione’s safety profile appears favorable, as it is commonly used in animal feed to support vitamin K production.
The findings suggest that menadione could be especially beneficial for prostate cancer patients under active surveillance, potentially delaying or even preventing progression.
With low side effects and a highly selective approach, this research offers new hope for effective, minimally invasive cancer treatment options.
Learn more:
Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function
www.science.org
Men taking antioxidant vitamin E supplements have increased prostate cancer (PC) risk. However, whether pro-oxidants protect from PC remained unclear. In this work, we show that a pro-oxidant vitamin ...
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AIGP Lawrence Nuwabiine Director TrafficThe Uganda Police Force (UPF) has reported a 4.1% decrease in crime rates, with reported cases dropping from 228,074 in 2023 to 218,715 in 2024, according to the Annual Crime Report 2024.This decline is attributed to enhanced community policing, digitisation of investigations, and the introduction of the Police Sub-County Model.During the Weekly Media Address at Police Headquarters in Naguru, key officials, including AIGP Tanui Stephen (Director of Fire and Rescue Services),
#Crimerate #Ugandapoliceforce
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Uganda Police Report 4.1% Decrease in Crime Rates
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AIGP Lawrence Nuwabiine Director Traffic The Uganda Police Force (UPF) has reported a 4.1% decrease in crime rates, with reported cases dropping from 228,074 in 2023 to 218,715 in 2024, according to t...We conducted a community outreach where we educated people about family planning and sexual reproductive health. We conducted interactive health talks with a focus on Family Planning and a considerable number chose different family planning methods including Sayana Press self-injection and more. #familyplanning #SRH
During a two-day health camp organised in partnership with the Kabaka Foundation and the Buganda Kingdom at St. Joseph’s Cathedral in Kyengera, 800 men were diagnosed with prostate cancer. This was part of a wider health initiative offering free screenings for various conditions, including diabetes and cataracts.
#Prostatecancer #Kabakahealthcamp
Comments: Very alarming results! It seems all men have prostate cancer. ... see more
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Doctors Alarmed as 800 Men Diagnosed with Prostate Cancer at Kabaka Health Camp in Just 2 Days
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During a two-day health camp organised by the Kabaka Foundation and the Buganda Kingdom at St. Joseph’s Cathedral in Kyengera, 800 men were diagnosed with prostate cancer. This was part of a wider h...